Kharaa is released and the Precursors initiate the planetary quarantine. However the parent tracks down its egg and rams into the Disease Research Facility, destroying it. The Precursors take a Sea Dragon Leviathan egg for research on leviathan egg hatching conditions, due to the species' possible relation to each other.The Precursors eventually place the remaining five eggs into the Incubator Device. More eggs from the majority of the species on the planet are taken as well. A second egg is stored within the Primary Containment Facility's egg lab in order to research it. The Precursors dissect one of the eggs and lay its fetus on an operating table, however, the process kills the fetus. The Sea Emperor Leviathan telepathically telling the Precursors their methods of forcefully making the eggs hatch would not work though according to the Sea Emperor "they could not hear".The Precursors then conclude to research its unborn eggs, as they deduced that a younger specimen would produce a stronger enzyme. Due to this, the potency of its Enzyme 42 had declined, meaning it was not capable of killing the infection, only causing temporary remission. It is revealed to the Precursors that their captive is much too old.It is likely that this is also when the Ancient Skeleton was discovered, and the Lost River Laboratory Cache was constructed as the focus of this laboratory's study is Leviathans. The Precursors capture a 1600-year-old Sea Emperor Leviathan, along with its seven eggs and contain them within the facility. After many tests, the Sea Emperor Leviathan species is found to have an immunity to Kharaa, and the Primary Containment Facility is constructed, along with the Alien Arch Caches in various biomes.It can be assumed that around this time period, the Gargantuan Fossil was found, and the Precursors began taking samples from its ribcage. The Quarantine Enforcement Platform, the Disease Research Facility, and the Alien Thermal Plant are constructed, as well as the Sanctuary Caches. T he Precursors set up several research outposts to attempt to develop a vaccine, including one on Planet 4546B.Errors in quarantine procedures cause Kharaa to be spread to their core worlds. Around 1000 years prior to the events of the game, the Precursor Race discovers Kharaa on an unknown planet and some individuals are infected.
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